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遗传与发育协同创新中心2017年度、2018年度“十大科技进展”评选结果

发布时间: 2019-06-06 17:27

    为充分展示遗传与发育协同创新中心在2017年、2018年的重大科技成果,推动科技创新,促进创新人才的发展,引领原创成果的产出,中心启动2017年度、2018年度“十大科技进展”评选活动。
    中心发展战略研究部分别从中心PI发表文章中推荐多篇(2017年31篇,2018年32篇)作为候选文章,邀请各学术研究部首席科学家、主任等资深专家对候选文章进行了函评投票,最后,按照得票顺序,遴选出2017年度、2018年度“十大科技进展”。
    经中心主任管理委员会讨论决定,给予“十大科技进展”每项成果的主要完成人2万元奖励,现将入选成果予以公布:

2017年度“十大科技进展”名单
1. 水稻高产优质性状形成的分子机理及品种设计.
2. m(6)A modulates haematopoietic stem and progenitor cell specification.
3. Epigenetic regulation of antagonistic receptors confers rice blast resistance with yield balance.
4. Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis.
5. 基因组拷贝数变异的突变机理与致病机制研究.
6. 3D Chromatin Structures of Mature Gametes and Structural Reprogramming during Mammalian Embryogenesis.
7. Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.
8. Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities.
9. 植物花药绒毡层细胞死亡和花粉外壁建成的分子机制.
10. Firmiana: towards a one-stop proteomic cloud platform for data processing and analysis.

2018年度“十大科技进展”名单
1. 遗传变异产生的分子基础.
2. The opium poppy genome and morphinan production.
3. Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations.
4. Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin.
5. Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation.
6. METTL3-mediated N-6-methyladenosine mRNA modification enhances long-term memory consolidation.
7. Structure of the mechanosensitive OSCA channels.
8. Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance.
9. Repression of human and mouse brain inflammaging transcriptome by broad gene-body histone hyperacetylation.
10. 3 ' UTR lengthening as a novel mechanism in regulating cellular senescence

遗传与发育协同创新中心
二零一九年六月六日